Effect of vitamin and feed supplement for the maintenance of reduced glutathione and sulfhydryl groups in the organs and tissues of rabbits

UDC 636.92:612.015

N. Rol,
S. Tsekhmistrenko

The purpose of the study is to study the effect of feed additive vitamin on the processes of lipid peroxidation in the body of rabbits. The main objectives of the study are the following: determination of reduced glutathione and sulfhydryl groups in heart, brain and in the longest muscle of the New Zealand rabbits breed after the use of vitamin and feed additive «Tekro». The SH-groups are chemically active groups that play an important role in cellular respiration, reactions of oxidative phosphorylation, regulation of membrane permeability. The SH-groups are part of the active centers of many enzymes and coenzymes, determine their catalytic activity, and are actively involved in maintaining tertiary structure of proteins. It is established that the use of vitamin and feed additive «Tekro» increases the glutathione content by 10.6% in brain tissues (probability value of p ≤ 0,05). In the heart of rabbits of 90-days age, the content of protein and total HS-groups is certainly increased by 7.9% and 2.5% respectively (probability value of p ≤ 0,01). The study of the longest back muscle showed that during the research period, the protein and total HS-groups content at the age of 90-days was 156,96 micromole/g and 169,44 micromole/g respectively. The obtained data of glutathione and sulfhydryl groups content in the body of rabbits is an important marker of oxidative stress. Determination of the dynamics of the antioxidant defense system can be used to detect oxidative stress in animals and to prevent its harmful impact on the body. The use of vitamin and feed additive «Tekro» in production of rabbits of New Zealand breed has a positive effect on the content of reduced glutathione and sulfhydryl groups in the brain, heart and longest back muscle

Effect of vitamin and feed supplement for the maintenance of reduced glutathione and sulfhydryl groups in the organs and tissues of rabbits.

Issue 1(88). 2016